Pubblications - GEIRD Study

Gene Environment Interactions in Respiratory Diseases
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Pubblications

PUBBLICAZIONI INTERNAZIONALI del GRUPPO GEIRD

PROTOCOLLO
  • The GEIRD Study Group (de Marco R, Accordini S, Antonicelli L, Bellia V, Bettin MD, Bombieri C, Bonifazi F, Bugiani M, Carosso A, Casali L, Cazzoletti L, Cerveri I, Corsico AG, Ferrari M, Fois AG, Lo Cascio V, Marcon A, Marinoni A, Olivieri M, Perbellini L, Pignatti P, Pirina P, Poli A, Rolla G, Trabetti E, Verlato G, Villani S, Zanolin ME) (2010) The Gene-Environment Interactions in Respiratory Diseases (GEIRD) Project. Int Arch Allergy Immunol, 152(3):255-263.

PREVALENZA delle MALATTIE RESPIRATORIE
  • de Marco R, Pesce G, Marcon A, Accordini S, Antonicelli L, Bugiani M, Casali L, Ferrari M, Nicolini G, Panico MG, Pirina P, Zanolin ME, Cerveri I, Verlato G (2013) The Coexistence of Asthma and Chronic Obstructive Pulmonary Disease (COPD). Prevalence and Risk Factors in Young, Middle-aged and Elderly People from the General Population. Plos one, 10;8(5):e62985

  • Pesce G, Marcon A, Carosso A, Antonicelli L, Cazzoletti L, Ferrari M, Fois AG, Marchetti P, Olivieri M, Pirina P, Pocetta G, Tassinari R, Verlato G, Villani S, de Marco R. Adult eczema in Italy: Prevalence and associations with environmental factors. J Eur Acad Dermatol Venereol 2015;29(6):1180-1187

  • Cazzoletti L, Ferrari M, Olivieri M, Verlato G, Antonicelli L, Bono R, Casali L, Cerveri I, Marchetti P, Pirina P, Rossi A, Villani S, de Marco R. The gender, age and risk factor distribution differs in self-reported allergic and non-allergic rhinitis. Allergy Asthma Clin Immunol 2015; 11: Article Number 36

  • Antonicelli L, Marchetti P, Accordini S, Bono R, Carosso A, Casali L, Cazzoletti L, Corsico A, Ferrari M, Fois A, Nicolini G, Olivieri M, Pirina P, Verlato G, Villani S, de Marco R. The heterogeneity hidden in allergic rhinitis and its impact on co-existing asthma in adults: a population-based survey. Int Arch Allergy Immunol 2015; 168(3): 205-212


TREND TEMPORALE delle MALATTIE RESPIRATORIE
  • de Marco R, Cappa V, Accordini S, Rava M, Antonicelli L, Bortolami O, Braggion M, Bugiani M, Casali L, Cazzoletti L, Cerveri I, Fois AG, Girardi P, Locatelli F, Marcon A, Marinoni A, Panico MG, Pirina P, Villani S, Zanolin ME, Verlato G, for the GEIRD study group (2012) Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010, Eur Respir J, 39:883-892

  • Accordini S, Corsico AG, Cerveri I, Antonicelli L, Attena F, Bono R, Casali L, Ferrari M, Fois A, Marchetti P, Pirina P, Tassinari R, Verlato G, de Marco R. Diverging trends of chronic bronchitis and smoking habits between 1998 and 2010. Respir Res 2013 Feb 8;14(1):16

  • Cazzoletti L, Corsico AG, Albicini F, Di Vincenzo EM, Gini E, Grosso A, Ronzoni V, Bugiani M, Pirina P, Cerveri I. The course of asthma in young adults: a population-based nine-year follow-up on asthma remission and control. PLoS One 2014 Jan 29;9(1):e86956.

  • Pesce G, Locatelli F, Cerveri I, Bugiani M, Pirina P, Johannessen A, Accordini S, Zanolin ME, Verlato G, de Marco R. Seventy years of asthma in Italy: age, period and cohort effects on incidence and remission of self-reported asthma from 1940 to 2010. PloS One 2015; 10(10): Article Number e0138570

  • Pesce G, Marcon A, Calciano L, Perret JL, Abramson MJ, Bono R, Bousquet J, Fois AG, Janson C, Jarvis D, Jõgi R, Leynaert B, Nowak D, Schlünssen V, Urrutia-Landa I, Verlato G, Villani S, Zuberbier T, Minelli C, Accordini S; Ageing Lungs in European Cohorts (ALEC) study. Time and age trends in smoking cessation in Europe. PLoS One. 2019 Feb 7;14(2):e0211976. doi: 10.1371/journal.pone.0211976. eCollection 2019

IMPATTO / GRAVITA’ delle MALATTIE RESPIRATORIE  
  • Marcon A, Girardi P, Ferrari M, Olivieri M, Accordini S, Bombieri C, Bortolami O, Braggion M, Cappa V, Cazzoletti L, Locatelli F, Nicolis M, Perbellini L, Sembeni S, Verlato G, Zanolin ME, de Marco R (2013) Mild asthma and chronic bronchitis seem to influence functional exercise capacity: a multi-case control study. Int Arch Allergy Immunol, 161(2):181-188

  • Accordini S, Corsico AG, Calciano L, Bono R, Cerveri I, Fois A, Pirina P, Tassinari R, Verlato G, de Marco R. The impact of asthma, chronic bronchitis and allergic rhinitis on all-cause hospitalizations and limitations in daily activities. A population-based observational study. BMC Pulmonary Medicine 2015; 15: Article Number 10

  • Calciano L, Corsico AG, Pirina P, Trucco G, Jarvis D, Janson C, Accordini S. Assessment of  asthma severity in adults with ever asthma: A continuous score. PLoS One 2017;12(5):e0177538.

COMORBIDITA’
  • Ferrari M, Pesce G, Marcon A, Vallerio P, Fratta Pasini AM, de Marco R. Rhinitis is associated with a greater risk of intermittent claudication in adults. Allergy 2014 Apr;69(4):472-8.

  • De Santi F, Zoppini G, Locatelli F, Finocchio E, Cappa V, Dauriz M, Verlato G. Type 2 diabetes is associated with an increased prevalence of respiratory symptoms as compared to the general populaton. BMC Pulmonary Medicine 2017; 17: 101

  • Ferrari M, Piccinno E, Marcon A, Marchetti P, Cazzoletti L, Pirina P, Battaglia S, Grosso A, Squillacioti G, Antonicelli L, Verlato G, Pesce G. Chronic bronchitis without airflow obstruction, asthma and rhinitis are differently associated with cardiovascular risk factors and diseases. PLoS One. 2019 Nov 7;14(11):e0224999.

FATTORI DI RISCHIO
Ambientali
  • Pesce G, Bugiani M, Marcon A, Marchetti P, Carosso A, Accordini S, Antonicelli L, Cogliani E, Pirina P, Pocetta G, Spinelli F, Villani S, de Marco R. Geo-climatic heterogeneity in self-reported asthma, allergic rhinitis and chronic bronchitis in Italy. Sci Total Environ 2016 Feb 15;544:645-52.

  • Marchetti P, Pesce G, Villani S, Antonicelli L, Ariano R, Attena F, Bono R, Bellisario V, Fois A, Gibelli N, Nicolis M, Olivieri M, Pirina P, Scopano E, Siniscalco C, Verlato G, Marcon A. Pollen concentrations and prevalence of asthma and allergic rhinitis in Italy: evidence from the GEIRD study. Sci Total Environ 2017; 584-585:1093-1099

Personali (gravidanza)
  • Grosso A, Locatelli F, Gini E, Albicini F, Tirelli C, Cerveri I, Corsico AG. The course of asthma during pregnancy in a recent, multicase-control study on respiratory health. Allergy Asthma Clin Immunol. 2018 Apr 17;14:16.

Fumo di sigaretta
  • Verlato G, Accordini S, Nguyen G, Marchetti P, Cazzoletti L, Ferrari M, Antonicelli L, Attena F, Bellisario V, Bono R, Briziarelli L, Casali L, Corsico AG, Fois A, Panico MG, Piccioni P, Pirina P, Villani S, Nicolini G, de Marco R. Socioeconomic inequalities in smoking habits are still increasing in Italy. BMC Public Health 2014; 14:879

  • Verlato G, Nguyen G, Marchetti P, Accordini S, Marcon A, Marconcini R, Bono R, Fois A, Pirina P, de Marco R. Smoking and new-onset asthma in a a prospective study on Italian adults. Int Arch Allergy Immunol 2016;170:149-157

  • Marcon A, Pesce G, Calciano L, Bellisario V, Dharmage SC, Garcia-Aymerich J, Gislasson T, Heinrich J, Holm M, Janson C, Jarvis D, Leynaert B, Matheson MC, Pirina P, Svanes C, Villani S, Zuberbier T, Minelli C, Accordini S; Ageing Lungs In European Cohorts study. Trends in smoking initiation in Europe over 40 years: A retrospective cohort study. PLoS One. 2018 Aug 22;13(8):e0201881.

Stress ossidativo
  • Zanolin ME, Girardi P, Degan P, Rava M, Olivieri M, Di Gennaro G, Nicolis M, De Marco R. Measurement of a urinary marker (8-hydroxydeoxy-guanosine, 8-OHdG) of oxidative stress in epidemiological surveys: a pilot study. Int J Biol Markers 2015 Jul 22;30(3):e341-5.

  • Chamitava L, Garcia-Larsen V, Cazzoletti L, Degan P, Pasini A, Bellisario V, Corsico AG, Nicolis M, Olivieri M, Pirina P, Ferrari M, Stasinopoulos MD, Zanolin ME. Determination of adjusted reference intervals of urinary biomarkers of oxidative stress in healthy adults using GAMLSS models. PLoS One. 2018 Oct 23;13(10):e0206176.

Altri fattori genetici e biomarker
  • Accordini S, Calciano L, Bombieri C, Malerba G, Belpinati F, Lo Presti AR, Baldan A, Ferrari M, Perbellini L, de Marco R. In Interleukin 13 Polymorphism is associated with symptom severity in adult subjects with ever asthma. PLoS One 2016 Mar 17;11(3):e0151292.

  • Calciano L, Portas L, Corsico AG, Olivieri M, Degan P, Ferrari M, Fois A, Fratta Pasini AM, Pasini A, Zanolin ME, de Marco R, Accordini S. Biomarkers related to respiratory symptoms and lung function in adults with asthma. J Breath Res 2018; 12(2): Article Number 026012

METODOLOGIA EPIDEMIOLOGICA

  • Johannessen A, Verlato G, Benediktsdottir B, Forsberg B, Franklin K, Thorarinn Gislason T, Holm M, Janson C, Jögi R, Lindberg E, Macsali F, Omenaas E, Real FG, Saure EW, Schlünssen V, Sigsgaard T, Skorge TD, Svanes C, Toren K, Waatevik MJ, Nilsen RN, de Marco R (2014) Long-term follow-up in European respiratory health studies - patterns and implications. BMC Pulmonary Medicine 2014; 14(1):63

Section of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health (DDSP) - University of Verona
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